Role of irisin in bone diseases

Bone diseases are common among middle-aged and elderly people, harm to activities of daily living (ADL) quality life (QOL) for patients. It is crucial search key regulatory factors associated with the development bone explore potential therapeutic targets diseases. Irisin a novel myokine that has been discovered in recent years. Accumulating evidence indicates irisin beneficial effects treatment various such as metabolic, cardiovascular neurological disorders, especially bone-related Recent studies had shown plays role osteoarthritis, osteoporosis other diseases, suggesting may be molecule prevention Therefore, this review, by consulting related domestic international literature we summarized specific mechanisms provided systematic theoretical basis its application diagnosis